Dawson RMC, Elliott DC, Elliott WH & Jones KM, 1986

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Dawson et al. report a complete set of amino acid pK values in the third edition of their text Data for Biochemical Research (1986) (1). The pK values they report are the pK values of the free amino acids as reported by Perrin (2,3).

Amino acid pK values from Dawson RMC, Elliott DC, Elliott WH & Jones KM, 1986 (1).

Group

2.15

†‡

ASP

3.90

†

GLU

4.07

†

HIS

6.04

†

9.52

†¶

CYS

8.37

†

TYR

10.46

†

LYS

10.54

†

ARG

12.48

†

† Data from Chapter I.

‡ This value is derived from these data by determining the mean value of the carboxylic acid pK values for the twenty amino acids.

¶ This value is derived from these data by determining the mean value of the amino group pK values for the twenty amino acids.

References

(1) Dawson RMC, Elliott DC, Elliott WH & Jones KM (1986) Data for Biochemical Research, Oxford University Press, Oxford

(2) Perrin DD (1969) Dissociation Constants of Organic Bases in Aqueous Solution, Butterworths, London

(3) Perrin DD (1972) Dissociation Constants of Organic Bases in Aqueous Solution: Supplement 1972, Butterworths, London